abstract：:The technical advances of the last century changed the understanding of the science of cutaneous physiology and pathology and the role of the dermatologist. The major challenges the international dermatologic community faces today are the lack of a common, logical, and accepted language within the specialty; long-acce...

journal_title：Dermatologic clinics

authors： Lotti T,Handog EB,Hercogová J,Ramos-E-Silva M

更新日期：2008-04-01 00:00:00

abstract：:This article provides a detailed review of the vascular manifestations affecting the skin in relationship to internal malignancies. Vascular abnormalities heralding internal malignancies can be divided into three main categories, consisting of disorders related to vascular dilatation (flushing, palmar erythema, and te...

journal_title：Dermatologic clinics

authors： El Tal AK,Tannous Z

更新日期：2008-01-01 00:00:00

abstract：:Contact dermatitis is a common skin disease caused by contact with irritants or allergens. Irritant contact dermatitis is a result of nonspecific irritant factors, which cause activation of mainly innate immunity, resulting in skin inflammation. Contact hypersensitivity, which manifests itself as allergic contact derm...

journal_title：Dermatologic clinics

authors： Fyhrquist-Vanni N,Alenius H,Lauerma A

更新日期：2007-10-01 00:00:00

abstract：:The vitamin D endocrine system is known for its essential role in calcium homeostasis and bone metabolism, and induces cell differentiation, inhibits cell growth, controls other hormonal systems, and modulates the immune response. Vitamin D(3) is a prohormone that is taken up by diet or synthesized in ultraviolet radi...

journal_title：Dermatologic clinics

authors： Carlberg C,Seuter S

更新日期：2007-10-01 00:00:00

abstract：:Countries in the so-called "Western" world, especially in Europe, witnessed a dramatic change in ethnic backgrounds of their populations starting in the last decennia of the last century. This had repercussions on various aspects of our society, including medical practice. In dermatology for instance, pigmentary disor...

journal_title：Dermatologic clinics

authors： van der Veen JP

更新日期：2007-07-01 00:00:00

abstract：:This article addresses pigmentary disorders relevant to India. Many of these disorders are easily spotted because of the Indians' darker complexion. The authors examine hypopigmentary and hyperpigmentary disorders, defining the main characteristics of each and their relevance to the people of India, including social a...

journal_title：Dermatologic clinics

authors： Pasricha JS,Khaitan BK,Dash S

更新日期：2007-07-01 00:00:00

abstract：:This article discusses ways to recognize and manage lymphomas and pseudolymphomas associated with drug exposure. Over the last 30 years, the classification of pseudolymphomas and lymphomas has undergone significant change, especially following the application of sophisticated immunostaining and gene rearrangement anal...

journal_title：Dermatologic clinics

authors： Albrecht J,Fine LA,Piette W

更新日期：2007-04-01 00:00:00

abstract：:Tetracyclines are known to exhibit multiple significant anti-inflammatory actions. This article describes the mechanisms of this anti-inflammatory activity, such as inhibition of chemotaxis, granuloma formation, and protease. The article also discusses the effectiveness of tetracyclines in treating such diseases as ac...

journal_title：Dermatologic clinics

authors： Webster G,Del Rosso JQ

更新日期：2007-04-01 00:00:00

abstract：:Photodynamic therapy (PDT) has had a rapid insurgence into the dermatologic armamentarium of clinicians from all over the world. Its use in actinic keratoses and in non-melanoma skin cancers is well described. Additional uses, including its use in the treatment of photorejuvenation and acne vulgaris and related disord...

journal_title：Dermatologic clinics

authors： Gold MH

更新日期：2007-01-01 00:00:00

abstract：:Light therapy is widely used in dermatology. An enhancement to his therapy is the use of a photosensitizing medication along with light therapy, known as photodynamic therapy (PDT). PDT is primarily used for the treatment of precancerous lesions, acne vulgaris, and nonmelonoma skin cancer, and has also been shown to i...

journal_title：Dermatologic clinics

authors： Nootheti PK,Goldman MP

更新日期：2007-01-01 00:00:00

abstract：:AIDS produces profound alterations in normal immunity. Impaired cellular immunity permits new tumor formation as evidenced by the solid-organ transplant literature. The weakened cellular immune system of HIV-infected patients resembles in some ways the iatrogenic immunosuppression in solid-organ transplant recipients....

journal_title：Dermatologic clinics

authors： Honda KS

更新日期：2006-10-01 00:00:00

abstract：:Though history will mark June 1981 as the birthday of the AIDS pandemic, the first true case of the syndrome and its cause originated years before in West-Central Africa. History also highlights the irony that the discovery of AIDS, the detection of its cause, and the development of drugs for its treatment, all occurr...

journal_title：Dermatologic clinics

authors： Colven R

更新日期：2006-10-01 00:00:00

abstract：:Nail pigmentation is defined by the presence of melanin in the nail plate. It most frequently has the appearance of a longitudinal pigmented band, called longitudinal mel-anonychia (LM). LM is an important aspect of ungual pathology because it can be the first sign of nail apparatus melanoma. The aim of this article i...

journal_title：Dermatologic clinics

authors： André J,Lateur N

更新日期：2006-07-01 00:00:00

abstract：:Osteoporosis affects more than 75 million people in the United States, Asia, and Europe. Osteoporosis results from a combination of genetic and environmental factors that contribute to peak bone mass and the rate of bone loss. These factors include medications, diet, race, sex, lifestyle, and physical activity. The ma...

journal_title：Dermatologic clinics

authors： Lamb A,Werth V

更新日期：2006-04-01 00:00:00

abstract：:Photoprotection as it pertains to hair is not a common topic addressed by the dermatologist. Hair is nonliving and requires no protection from ultraviolet (UV) radiation because carcinogenesis of the hair shaft itself is not possible. If hair proteins are altered by sun exposure, damaged hair can be removed and replac...

journal_title：Dermatologic clinics

authors： Draelos ZD

更新日期：2006-01-01 00:00:00

abstract：:The skin and the nervous system develop side by side in the fetus and remain intimately interconnected and interactive throughout life. Because of the skin-nervous system interactions, there is a significant psychosomatic or behavioral component to many dermatologic conditions. This permits complementary nonpharmacolo...

journal_title：Dermatologic clinics

authors： Shenefelt PD

更新日期：2005-10-01 00:00:00

abstract：:Many older individuals use products and procedures to conceal or delay the signs of aging. For most, this provides a helpful ego boost, but some suffer from pathologies such as eating disorders and body dysmorphic disorder. The impact of aging skin may include social anxiety and social isolation. Poor self-image is as...

journal_title：Dermatologic clinics

authors： Gupta MA,Gilchrest BA

更新日期：2005-10-01 00:00:00

abstract：:In the past decade, midface rejuvenation has matured to allow experienced surgeons to address this area as part of a total facial rejuvenation. Procedures have advanced as successive generations of surgeons have improved understanding of this complex anatomic area. Midface rejuvenation is fraught with perils, however,...

journal_title：Dermatologic clinics

authors： Finn JC

更新日期：2005-07-01 00:00:00

abstract：:To remain experts in skin care and treatment, every dermatologist must be aware of the evolving role of soft tissue fillers in dermatology. Patients with facial scarring, lipodystrophy, contour abnormalities, and age- and sun-induced rhytids can be successfully treated. A literature review, industry recommendations, a...

journal_title：Dermatologic clinics

authors： Murray CA,Zloty D,Warshawski L

更新日期：2005-04-01 00:00:00

abstract：:Cyanoacrylates (CAs) were not widely adopted for medical use until recently because of lingering concerns regarding the initial tissue toxicities of the short-chain CAs. The medium-chain CAs, primarily butyl-cyanoacrylate, have been widely used in Europe and Canada for several decades and have gone a long way in dispe...

journal_title：Dermatologic clinics

authors： Eaglstein WH,Sullivan T

更新日期：2005-04-01 00:00:00

abstract：:Nasal reconstruction can be challenging due to the complex nature of multiple cosmetic units and functional considerations. This article discusses single- and two-staged melolabial flap repairs for nasal reconstruction following removal of skin cancers. ...

journal_title：Dermatologic clinics

authors： Carucci JA

更新日期：2005-01-01 00:00:00

abstract：:It is quite evident the pathogenesis of psoriasis is modulated by immune-mediated mechanisms that invoke activated T cells and inflammatory cytokines, such as tumor necrosis factor-alpha. Current immunosuppressive systemic treatments may be effective in controlling psoriasis to a certain degree but have significant dr...

journal_title：Dermatologic clinics

authors： Yamauchi PS,Gindi V,Lowe NJ

更新日期：2004-10-01 00:00:00

abstract：:The term viral hemorrhagic fever refers to a clinical syndrome characterized by acute onset of fever accompanied by nonspecific findings of malaise, prostration, diarrhea,and headache. Patients frequently show signs of increased vascular permeability, and many develop bleeding diatheses. The hemorrhagic fever viruses ...

journal_title：Dermatologic clinics

authors： Salvaggio MR,Baddley JW

更新日期：2004-07-01 00:00:00

abstract：:This article discusses complications with the use of botulinum toxin. The following topics are explored: conditions caused by muscle spasms, resistance to botulinum toxin, cosmetic use of botulinum toxin, complications in treating hyperhidrosis, treatment of migraine headaches, and informed consent. ...

journal_title：Dermatologic clinics

authors： Klein AW

更新日期：2004-04-01 00:00:00

abstract：:Dermatologic infections are treated to improve the elderly patient's quality of life and prevent disability and death. Pharmacokinetic changes, social issues, and the risk for adverse effects and drug interactions, however, increase the challenge to achieve successful treatment of those over age 65 as compared with yo...

journal_title：Dermatologic clinics

authors： Hutchison LC

更新日期：2004-01-01 00:00:00

abstract：:Native Americans have a rich and complex heritage and culture. Although the genetic pool has changed with increasing integration with other Americans with different ancestry, there are important conditions that are unique to Native Americans, the most prominent example being actinic prurigo. The scientific literature ...

journal_title：Dermatologic clinics

authors： Cornelison RL Jr

更新日期：2003-10-01 00:00:00

abstract：:Differences have been found among blacks, whites, Asians, and Hispanics in various areas of skin structure and function. Among them is the stratum corneum lipid (ceramide) content, which is highest in Asians, then Hispanics, then whites, and lowest in blacks. Melanosomal packaging and percutaneous absorption rates for...

journal_title：Dermatologic clinics

authors： Richards GM,Oresajo CO,Halder RM

更新日期：2003-10-01 00:00:00

abstract：:The management of onychomycosis using topical agents has improved with the introduction of ciclopirox and amorolfine nail lacquers; other topical agents may be less effective. The combination of a nail lacquer with an oral antifungal agent may further improve efficacy rates in certain clinical presentations (eg, among...

journal_title：Dermatologic clinics

authors： Gupta AK,Ryder JE,Baran R

更新日期：2003-07-01 00:00:00

abstract：:Ivermectin is a potent antiparasitic drug and the first commercially available member of a new class of drugs (macrocyclic lactones) that has been approved for human use. Ivermectin has already proven to be highly effective in the elimination of river blindness as a public health burden. Side effects have been minor, ...

journal_title：Dermatologic clinics

authors： Elgart GW,Meinking TL

更新日期：2003-04-01 00:00:00

abstract：:Many genodermatoses have distinct oral features that may help identify or confirm a genetic diagnosis. Oral features of the disorders described here are summarized in Table 1. These conditions provide clear examples of rapid progress in the field of genetic technology relevant to patient care. Less than a decade ago, ...

journal_title：Dermatologic clinics

authors： Hand JL,Rogers RS 3rd

更新日期：2003-01-01 00:00:00

abstract：:The progress in research on OLP and other autoimmune diseases has been significant. Coupled with a growing recognition of the clinical features and treatment options by dentists and physicians and fueled by the advances in immunosuppressive therapies, research will undoubtedly provide new insights into this complex di...

journal_title：Dermatologic clinics

authors： Eisen D

更新日期：2003-01-01 00:00:00

abstract：:This article describes that the diagnosis of melanoma has improved with such tools as epiluminescence microscopy. There remain, however, a number of unusual types of melanoma that are difficult to diagnose by virtue of their atypical or subtle morphology. The prognosis of these melanomas is often worse than for their ...

journal_title：Dermatologic clinics

authors： Rivers JK

更新日期：2002-10-01 00:00:00

abstract：:This article describes major screening studies of the past two decades, discusses the evidence-based screening recommendations, highlights the need to screen high-risk and previously unscreened populations, and concludes with suggestions for risk assessment and physician-nurse training in the skin cancer examination. ...

journal_title：Dermatologic clinics

authors： Geller AC

更新日期：2002-10-01 00:00:00

abstract：:Cutaneous manifestations of thyroid disease are protean in nature and can be divided into specific lesions such as the thyroglossal duct cyst and cutaneous metastases from thyroid malignancy, nonspecific signs secondary to thyroid hormone imbalance, and associated dermatologic and systemic disorders. This review repre...

journal_title：Dermatologic clinics

authors： Leonhardt JM,Heymann WR

更新日期：2002-07-01 00:00:00

abstract：:Infections by VZV, the virus that causes chickenpox and herpes zoster, usually are diagnosed by the classic clinical presentations. In immunocompromised patients, however, the atypical presentation can make the diagnosis more challenging. Although varicella typically follows an uncomplicated course in children, adults...

journal_title：Dermatologic clinics

authors： Chen TM,George S,Woodruff CA,Hsu S

更新日期：2002-04-01 00:00:00

abstract：:Laser skin surgery is not without risk and some degree of downtime in most situations. Patient satisfaction is key to the perceived success of the procedure. Therefore, the physician must fully explain all risks, potential complications, and expected morbidity associated with any laser treatment to be performed. Altho...

journal_title：Dermatologic clinics

authors： McBurney EI

更新日期：2002-01-01 00:00:00

abstract：:Among the different classes and complexities of antiretroviral regimens, maximal viral suppression, sustained durability, increased CD4 count, decreased evolving resistance, and fewer side effects combined with increased compliance resulting in decreased morbidity and mortality remain the goals of therapy. Serial vira...

journal_title：Dermatologic clinics

authors： Carrasco DA,Tyring SK

更新日期：2001-10-01 00:00:00

abstract：:Since its discovery, the understanding of the roles for TNF-alpha in human biology and disease has grown. Receptors for TNF are found on virtually all cell types, and many physiologic processes seem to be altered by TNF-alpha. The understanding of how TNF-alpha is involved in the pathophysiology of diseases, such as i...

journal_title：Dermatologic clinics

authors： LaDuca JR,Gaspari AA

更新日期：2001-10-01 00:00:00

abstract：:Large defects may at first appear to be too big to close in a side-to-side fashion. Certain wounds and situations may call for healing with second intent. Undermining and pulley sutures are very helpful in bringing together wound edges of certain large openings. Partial closures may decrease the tendency to exert unwa...

journal_title：Dermatologic clinics

authors： Shelton RM

更新日期：2001-07-01 00:00:00

abstract：:This article provides an overview of the resurfacing technique of dermabrasion. Preoperative consultation, perioperative medications, postoperative management, common complications, and reasonable outcome expectations are all described in detail. A description of proper technique, intraoperative equipment, and an appr...

journal_title：Dermatologic clinics

authors： Harmon CB

更新日期：2001-07-01 00:00:00